CD11c is the 150 kDa (Y-chain of the leucocyte integrin complex P1 50,95. The protein belongs to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens. The CD11 family shares a common 95 kDa li-chain (CD18). In addition to the p150,95 protein, this protein family contains two other members: leucocyte function associated-1 antigen (LFA-1, CD11a) and iC3b receptor (CD11b) (Hogg, 1997). CD11c is expressed strongly on monocytes and weakly on neutrophil granulocytes (Hogg, 1997). Natural killer cells and activated B and T cells also express CD11c (Luk, 1995). Anti-CD11c, KB90, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD11c antigen (Hogg, 1997).

Antibody recognizes Human CD11c antigen.

Hairy cell leukemia cells

Milli-Mark Anti-CD11c-FITC Antibody, clone KB90 is an antibody against CD11c for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Evaluated by flow cytometry using human PBMCs

150 kDa (Hogg, 1997)

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Control
PBMCs

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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