About This Item
species reactivity
human
Quality Level
assay range
accuracy: 88-97%, standard curve range: 137-100,000 pg/mL
(Thrombospondin-2), standard curve range: 137-100,000 pg/mL
(sVEGFR2), standard curve range: 137-100,000 pg/mL
(suPAR), standard curve range: 14-10,000 pg/mL
(sAXL), standard curve range: 14-10,000 pg/mL
(sHER3), standard curve range: 14-10,000 pg/mL
(sVEGFR1), standard curve range: 27-20,000 pg/mL
(sIL-6Rα), standard curve range: 27-20,000 pg/mL
(sPECAM-1), standard curve range: 27-20,000 pg/mL
(sTIE-2), standard curve range: 274-200,000 pg/mL
(Angiostatin), standard curve range: 274-200,000 pg/mL
(sE-Selectin), standard curve range: 274-200,000 pg/mL
(sNeuropilin-1), standard curve range: 41-30,000 pg/mL
(Osteopontin (OPN)), standard curve range: 41-30,000 pg/mL
(sEGFR), standard curve range: 41-30,000 pg/mL
(sHER2), standard curve range: 41-30,000 pg/mL
(sc-Kit/sSCFR), standard curve range: 412-300,000 pg/mL
(sVEGFR3), standard curve range: 69-50,000 pg/mL
(sHGFR), standard curve range: 7-5,000 pg/mL
(PDGF-AB/BB)
technique(s)
multiplexing: suitable
input
serum plasma (Cell culture, cell culture supernatants)
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
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General description
Application
Analytes included: Angiostatin, soluble E-Selectin, (sE-Selectin), Osteopontin (OPN), Platelet Derived Growth Factor-AB/BB (PDGF-AB/BB), soluble Platelet Endothelial Cell Adhesion Molecule-1 (sPECAM-1), Thrombospondin-2 (TSP-2), soluble AXL (sAXL), soluble c-Kit/Stem Cell Growth Factor Receptor (sc-Kit/SCFR), soluble Epidermal Growth Factor Receptor (sEGFR)†, soluble Human Epidermal Growth Factor Receptor 2 (sHer2), soluble Human Epidermal Growth Factor Receptor 3 (sHer3), soluble Hepatocyte Growth Factor Receptor/c-Met (sHGFR/c-Met), soluble IL-6Rα, soluble Neuropilin-1 (sNRP-1), soluble Tie-2 (sTie-2), soluble Urokinase-type Plasminogen Activator Receptor (suPAR), soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1), soluble Vascular Endothelial Growth Factor Receptor 2 (sVEGFR2), and soluble Vascular Endothelial Growth Factor Receptor 3 (sVEGFR3)†Antibody against active site results in preferential binding to unbound EGFR.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Comprehensive Insights into Angiogenesis: By measuring multiple angiogenic factors simultaneously, researchers can gain a deeper understanding of the balance between pro-angiogenic and anti-angiogenic signals, crucial for studying diseases like cancer, cardiovascular conditions, and diabetic ulcers.
- Flexible Research Applications: Ideal for studying cancer biology, wound healing, and other conditions influenced by angiogenesis, this panel supports a wide range of investigative goals in the field of vascular biology.
- Configurable Multiplexing Options: Researchers can design their multiplex kit by selecting from the available analytes within the panel, tailoring the assay to meet specific research needs and objectives.
- 19-Plex Capability: This advanced kit allows for the simultaneous quantification of 19 critical analytes related to angiogenesis, including Angiostatin, soluble E-Selectin, Osteopontin, PDGF-AB/BB, and various soluble growth factor receptors, providing a comprehensive overview of angiogenic activity.
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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