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HIFN-130K-PMX9

MILLIPLEX® Human Interferon Panel

Premixed Human Interferon 9-Plex Panel

Synonym(s):

Human Cytokine Panel

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About This Item

NACRES:
NA.77
UNSPSC Code:
12161503

Key Documents

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Quality Level

200

technique(s)

multiplexing: suitable

input

cell culture supernatant
serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

usage

-1 kit -96 wells

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

parameter

-25 μL sample volume (per well)

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General description

Interferons (IFNs) are widely expressed cytokines that have potent antiviral and antiproliferative effects. These cytokines are the first line of defense against viral infections and have important roles in immunosurveillance for malignant cells. IFNs are classified as type I, II and III IFNs, based upon the target receptors to which they bind. In humans, type I IFNs belong to a multigene family consisting of multiple IFNα subtypes but only one IFNβ, IFNε, IFNκ, and IFNψ. There is only one type II IFN: IFNγ. The type III IFNs include IFNλ1, λ2 and λ3, which are also known as interleukin-29 (IL-29), IL 28A and IL-28B, respectively. Functionally, the type I and type III IFNs are induced during a viral infection and involved in host defense against viruses. IFNγ (type II) is primarily involved in the allergic response, in host defense against intracellular pathogens, and in control of tumor growth. Studies of IFNs have broadened the mechanistic understanding of cell signaling, gene transcription, and innate and acquired immunity.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 9 analytes in human serum or plasma samples and tissue/cell lysate and culture supernatants.

Analytes included: IFNα-2, IFNβ, IFNε, IFNɣ, IFNɣ Receptor 1, IFNλ1, IFNλ2, IFNλ3, IFNψ

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Ready-to-Use Convenience: Streamline your workflow with pre-optimized 9-plex premixed reagents, eliminating time-consuming optimization steps for immediate interferon quantification in viral infection and tumor immunosurveillance studies.
  • Simplified Laboratory Operations: Reduce hands-on time and potential errors with convenient premixed format, perfect for high-throughput screening of antiviral responses and immunomodulatory research applications.
  • Innate & Adaptive Immunity Investigation: Advance mechanistic understanding of cell signaling, gene transcription, and immune responses by measuring key interferon mediators across innate and acquired immunity pathways.
  • Luminex® xMAP® Technology Advantage: Leverage proven magnetic bead-based multiplex immunoassay technology for sensitive, specific, and simultaneous quantification of multiple interferon analytes using established Luminex® instrumentation platforms.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 3

Regulatory Information

新产品
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