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HIL18MAG-66K

MILLIPLEX® Human IL-18 Singleplex

Human IL-18 Singleplex Kit

Synonym(s):

Magnetic bead assay

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
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Product Name

MILLIPLEX® Human IL-18 Singleplex, Human IL-18 Singleplex Kit

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

input

serum
cell culture supernatant

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Analyze IL-18 in human serum, plasma, and cell culture supernatants.

Analytes included: IL-18

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Facilitates Biomarker Discovery: Useful in studying diseases where IL-18 plays a role, such as autoimmune disorders, infections, and cancer.User-Friendly: The straightforward protocol makes it accessible even for labs with limited experience in cytokine assays.Multiplexing Flexibility: The IL-18 kit can be combined with other MILLIPLEX® kits, allowing for the simultaneous measurement of multiple cytokines and biomarkers in a single sample.

General description

Interleukin-18 (IL-18) is a pro-inflammatory cytokine that plays a crucial role in the immune response by promoting the activation and proliferation of T cells and natural killer (NK) cells. It is primarily produced by macrophages and dendritic cells and is involved in various physiological processes, including inflammation, infection, and autoimmune diseases. Elevated levels of IL-18 have been associated with several conditions, such as cardiovascular diseases, cancer, and chronic inflammatory disorders, making it an important biomarker for research and therapeutic targets.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

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Chuanhai Cao et al.
Frontiers in aging neuroscience, 14, 829049-829049 (2022-05-20)
The immune system plays a critical role in the development and progression of Alzheimer's disease (AD). However, there is disagreement as to whether development/progression of AD involves an over-activation or an under-activation of the immune system. In either scenario, the
Gyoung Nyoun Kim et al.
PLoS pathogens, 17(12), e1010092-e1010092 (2021-12-17)
The development of safe and effective vaccines to prevent SARS-CoV-2 infections remains an urgent priority worldwide. We have used a recombinant vesicular stomatitis virus (rVSV)-based prime-boost immunization strategy to develop an effective COVID-19 vaccine candidate. We have constructed VSV genomes
Devalingam Mahalingam et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(1), 71-81 (2019-11-07)
Pelareorep is an intravenously delivered oncolytic reovirus that can induce a T-cell-inflamed phenotype in pancreatic ductal adenocarcinoma (PDAC). Tumor tissues from patients treated with pelareorep have shown reovirus replication, T-cell infiltration, and upregulation of PD-L1. We hypothesized that pelareorep in

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