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MABD146

Anti-Lefty Antibody, clone 1G9.1

clone 1G9.1, from mouse

Synonym(s):

Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.75

Key Documents

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

1G9.1, monoclonal

species reactivity

rat, mouse

technique(s)

western blot: suitable

isotype

IgMκ

NCBI accession no.

NP_066277

UniProt accession no.

O75610

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... LEFTY1(10637)

General description

Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.
~40 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.

Application

Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.
Research Category
Stem Cell Research
Research Sub Category
Cell Cycle, DNA Replication & Repair
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.

Physical form

Format: Purified
Purified by Ion-Exchange Chromatography
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in L6 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.
Replaces: MABD186

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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