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NHPMHMAG-45K

MILLIPLEX® Non-Human Primate Metabolic Panel

Configurable Non-Human Primate Metabolic 12-Plex Panel

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Non-Human Primate Metabolic Panel, Configurable Non-Human Primate Metabolic 12-Plex Panel

species reactivity

nonhuman primates

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 102%
(Ghrelin (Active))
accuracy: 91%
(Insulin)
accuracy: 93%
(GLP-1)
accuracy: 94%
(PP)
accuracy: 98%
(MCP-1)
accuracy: 99%
(Leptin)
sensitivity: 0.6-65.1 pg/mL
standard curve range: 13.7-10,000 pg/mL
(Ghrelin (Active), GLP-1, Glucagon, IL-6, MCP-1, PP, PYY)
standard curve range: 137.2-100,000 pg/mL
(Insulin, Leptin)
standard curve range: 2.7-2,000 pg/mL
(GIP)
standard curve range: 27.4-20,000 pg/mL
(Amylin)
standard curve range: 68.6-50,000 pg/mL
(C-Peptide)
inter-assay cv: <15%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 12 analytes in non-human primate serum, plasma, or cell culture supernatants.

Analytes included: Amylin (active), C-Peptide, Ghrelin (active), GIP (total), GLP-1 (active), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total) Note: Some analytes require a protease inhibitor during sample collection.

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Targets key metabolic hormones and inflammatory markers relevant to energy regulation and glucose metabolism
  • Includes 12 analytes covering appetite control, insulin dynamics, and immune-metabolic signaling
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with non-human primate serum, plasma, and tissue culture supernatant samples
  • Designed for metabolic, obesity, diabetes, and inflammation research in primate models
Benefits:

  • Provides a comprehensive profile of endocrine and metabolic function in non-human primates
  • Supports evaluation of therapeutic interventions targeting appetite, insulin sensitivity, and inflammation
  • Facilitates monitoring of hormonal responses to dietary, pharmacological, or genetic manipulations
  • Enhances understanding of metabolic disease mechanisms in translational research
  • Streamlines experimental workflows with high-throughput, multi-analyte capability

General description

Metabolic hormones such as amylin, C-peptide, ghrelin, GIP, GLP-1, glucagon, insulin, leptin, pancreatic polypeptide (PP), and PYY are central to regulating energy balance, appetite, and glucose metabolism in non-human primates. Amylin complements insulin in controlling blood glucose, while C-peptide reflects endogenous insulin production. Ghrelin stimulates hunger, and GLP-1 and GIP enhance insulin secretion post-meal. Glucagon raises blood glucose levels, and leptin signals satiety. PP and PYY modulate digestive processes and appetite. IL-6 and MCP-1/CCL2 provide insight into inflammation and immune-metabolic interactions. Together, these biomarkers offer a comprehensive view of metabolic health and endocrine function in preclinical primate models.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

新产品
This item has

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Julia L Nugent et al.
iScience, 24(12), 103421-103421 (2021-12-09)
The obesity epidemic significantly contributes to overall morbidity and mortality. Bariatric surgery is the gold standard treatment for obesity and metabolic dysfunction, yet the mechanisms by which it exerts metabolic benefit remain unclear. Here, we demonstrate a model of vertical
Eliete Dalla Corte Frantz et al.
PloS one, 8(7), e67192-e67192 (2013-07-31)
The associations between obesity, hypertension and diabetes are well established, and the renin-angiotensin system (RAS) may provide a link among them. The effect of RAS inhibition on type 2 diabetes is still unclear; however, RAS seems to play an important

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Protocol- NHPMHMAG-45K
Quality Control Ranges: Milliplex Human Metabolic Hormone Panel, Milliplex Human Metabolic Hormone Magnetic Panel, Milliplex Non-Human Metabolic Magnetic Bead Panel
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