MILLIPLEX^® Rat Vascular Injury Panel

Vascular injury triggers a cascade of inflammatory and immune responses, reflected in the expression of key plasma proteins such as α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin (A2M), and Haptoglobin. AGP is an acute phase reactant that modulates immune activity and vascular permeability. A2M functions as a broad-spectrum protease inhibitor, playing a role in tissue protection and repair. Haptoglobin binds free hemoglobin released during vascular damage, preventing oxidative stress and supporting clearance. Together, these analytes provide insight into vascular integrity, inflammation, and tissue recovery in rat models.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 3 analytes in rat serum or plasma samples.

Analytes included: α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin (A2M), Haptoglobin

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features:

• Targets key biomarkers associated with vascular injury and acute phase response
• Includes AGP, A2M, and Haptoglobin for comprehensive vascular profiling
• Multiplex format enables simultaneous detection from minimal sample volume
• Compatible with rat serum, plasma, and tissue culture supernatant samples
• Designed for vascular injury, inflammation, and tissue repair research

Benefits:

• Provides molecular insight into vascular damage and systemic inflammatory response
• Supports evaluation of therapeutic interventions targeting vascular protection
• Facilitates monitoring of acute phase reactants in preclinical rat models
• Enhances understanding of tissue remodeling and oxidative stress mechanisms
• Streamlines experimental workflows with high-throughput, multi-analyte capability

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.