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Merck
CN

01-6010

Potassium antimonyl tartrate trihydrate

JIS special grade, ≥99.5%

Synonym(s):

Antimony potassium tartrate trihydrate, Tartar emetic

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About This Item

Empirical Formula (Hill Notation):
C8H4K2O12Sb2 · 3H2O
CAS Number:
28300-74-5
Molecular Weight:
667.87
UNSPSC Code:
12352103
PubChem Substance ID:
329747331
EC Number:
234-293-3
MDL number:
MFCD00167056

Key Documents

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InChI key

WBTCZEPSIIFINA-UHFFFAOYSA-J

InChI

1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4

SMILES string

O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O

grade

JIS special grade

assay

≥99.5%

form

powder

availability

available only in Japan

pH

4 (20 °C)

mp

≥300 °C (lit.)

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pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
U5238
U2275
U1367
U2479
U1543

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Xiang Ruan et al.
The Journal of biological chemistry, 281(15), 9925-9934 (2006-02-10)
The arsRDABC operon of Escherichia coli plasmid R773 encodes the ArsAB extrusion pump for the trivalent metalloids As(III) and Sb(III). ArsA, the catalytic subunit has two homologous halves, A1 and A2. Each half has a consensus signal transduction domain that
Case records of the Massachusetts General Hospital. Case 22-2012. A 34-year-old man with intractable vomiting after ingestion of an unknown substance.
Wendy Macías Konstantopoulos et al.
The New England journal of medicine, 367(3), 259-268 (2012-07-20)
P Holzmuller et al.
Antimicrobial agents and chemotherapy, 49(10), 4406-4409 (2005-09-29)
We previously documented the induction of Leishmania amastigote apoptosis by trivalent antimony (SbIII) and nitric oxide (NO). We demonstrate here that SbIII-resistant amastigotes were resistant to NO toxicity when delivered extracellularly by NO donors or intracellularly via macrophage activation. Shared
Naira R Maciel et al.
Toxicology letters, 199(3), 234-238 (2010-09-15)
Trivalent antimonial drugs, including tartar emetic (TA), are known to induce important cardiotoxicity observed by electrocardiographic abnormalities. Liposome encapsulation was found to reduce the overall acute toxicity of TA. The present work investigated the cardiovascular parameters alterations of rats submitted
K Aït-Oudhia et al.
Veterinary parasitology, 187(3-4), 386-393 (2012-02-22)
The aim of this study was to evaluate the susceptibility to anti-leishmanial agents of 24 strains isolated from dogs living in the urban area of Alger lacking drug selection pressure. Two different Leishmania infantum zymodemes, MON-1 and MON-281, were identified
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