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Merck
CN

15235

N,N-Bis(trimethylsilyl)methylamine

derivatization grade (GC derivatization), LiChropur, ≥97.0% (GC)

Synonym(s):

Heptamethyldisilazane

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About This Item

Empirical Formula (Hill Notation):
C7H21NSi2
CAS Number:
Molecular Weight:
175.42
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-061-5
Beilstein/REAXYS Number:
1737290
MDL number:
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Product Name

N,N-Bis(trimethylsilyl)methylamine, derivatization grade (GC derivatization), LiChropur, ≥97.0% (GC)

InChI key

ZSMNRKGGHXLZEC-UHFFFAOYSA-N

InChI

1S/C7H21NSi2/c1-8(9(2,3)4)10(5,6)7/h1-7H3

SMILES string

CN([Si](C)(C)C)[Si](C)(C)C

grade

derivatization grade (GC derivatization)

assay

≥97.0% (GC)

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.421 (lit.)

bp

144-147 °C (lit.)

density

0.799 g/mL at 20 °C (lit.)

Quality Level

General description

N,N-Bis(trimethylsilyl)methylamine is a silylating agent used to prepare TMS derivatives. It has about the same silylation potential as hexamethyldisilazane (HMDS) and can be used in the same manner. Its reaction by-product is the gaseous methylamine.

Other Notes

Reagent for methylamination of acid halides, e.g. a phosphorus fluoride

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

82.4 °F - closed cup

flash_point_c

28 °C - closed cup

Regulatory Information

危险化学品
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M. Meyer et al.
Chemische Berichte, 121, 627-627 (1988)

Articles

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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