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PHR1266

Acesulfame K

Name: Acesulfame K
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Acesulfame potassium salt, 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt

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About This Item

Empirical Formula (Hill Notation):

C₄H₄KNO₄S

CAS Number:

55589-62-3

Molecular Weight:

201.24

NACRES:

NA.24

E Number:

E950

PubChem Substance ID:

329823262

UNSPSC Code:

41116107

EC Number:

259-715-3

MDL number:

MFCD00043833

Beilstein/REAXYS Number:

3637857

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Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. A0070000, traceable to USP 1002505

API family

acesulfame

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

[K+].CC1=CC(=O)[N-]S(=O)(=O)O1

InChI

1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1

InChI key

WBZFUFAFFUEMEI-UHFFFAOYSA-M

Description

General description

Acesulfame K is a synthetically prepared sulfonyl amide sweetener, widely used with sugar alcohols in food and beverage industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acesulfame K may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone electrophoresis and ion chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

To see an example of a Certificate of Analysis for this material enter LRAC1663 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bitter taste receptors for saccharin and acesulfame K

The Journal of Neuroscience, 24(45), 10260-10265 (2004)

Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography

Chen C-Q and Wang J

Journal of Chromatography A, 937(1-2), 57-64 (2001)

Biotechnology and Food Ingredients (1991)

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Global Trade Item Number

SKU	GTIN
PHR1266-500MG	04061834415527