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PHR1304

Butylated hydroxyanisole

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA

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About This Item

Linear Formula:
(CH3)3CC6H3(OCH3)OH
CAS Number:
25013-16-5
Molecular Weight:
180.24
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
246-563-8
MDL number:
MFCD01779059
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Quality Segment

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. B1212000, traceable to USP 1083008

vapor density

6.2 (vs air)

API family

butylhydroxyanisole

CofA

current certificate can be downloaded

autoignition temp.

599 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

58-60 °C (lit.)

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

O(C)c1cc(c(cc1)O)C(C)(C)C

InChI

1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3

InChI key

MRBKEAMVRSLQPH-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Butylated hydroxyanisole (BHA) may be used as a reference standard for the determination of the analyte in pharmaceutical creams by spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB3751 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Hazard Codes

H319,H411

Storage Class

11 - Combustible Solids

Flash Point (°F)

241.9 °F - Pensky-Martens closed cup

Flash Point (°C)

116.6 °C - Pensky-Martens closed cup

Signal Word

Warning

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2

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Certificates of Analysis (COA)

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