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PHR1348

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Saccharin Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Saccharin sodium, Saccharin sodium salt
Empirical Formula (Hill Notation):
C7H4NNaO3S
CAS Number:
Molecular Weight:
205.17

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. S0050000
traceable to USP 1607040

API family

saccharin

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

InChI

1S/C7H5NO3S.Na/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;/h1-4H,(H,8,9,10,11);/q;+1/p-1

InChI key

OAZGZMKGRPRHJX-UHFFFAOYSA-M

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General description

Saccharin Sodium is used as a sweetening and flavoring agent in food products and beverages. It is also used for masking unpleasant taste in pharmaceutical formulations such as tablets and powders. Its sweetening power is approximately 300 times more than sucrose.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.

Application

Saccharin Sodium may be used as a reference standard for the determination of the analyte in pharmaceuticals by continuous flow spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA1100 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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Linnea E Herzog et al.
Current biology : CB, 30(7), 1306-1311 (2020-03-21)
Animals need to remember the locations of nourishing and toxic food sources for survival, a fact that necessitates a mechanism for associating taste experiences with particular places. We have previously identified such responses within hippocampal place cells [1], the activity
Continuous flow spectrophotometric determination of paracetamol in pharmaceuticals following continuous microwave assisted alkaline hydrolysis
Criado A, et al.
Talanta, 53(2), 417-423 (2000)
Saccharin
Encyclopedia of Food and Color Additives, , year=, 3153-3153 (1997)
Saccharin
Encyclopedia of Food Sciences and Nutrition (Second Edition), 5033-5035 (2003)
Saccharin
Encyclopedia of Food and Color Additives, , year=, 3153-3153 (1997)

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