SMB00972
Potassium phenyl sulfate
Synonym(s):
Phenyl potassium sulfate
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About This Item
Empirical Formula (Hill Notation):
C6H5KO4S
CAS Number:
Molecular Weight:
212.26
UNSPSC Code:
41116105
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Solubility:
water: soluble
SMILES string
[K+].[S](=O)(=O)([O-])Oc1ccccc1
InChI
1S/C6H6O4S.K/c7-11(8,9)10-6-4-2-1-3-5-6;/h1-5H,(H,7,8,9);/q;+1/p-1
InChI key
NOUFXYHWAWIDNT-UHFFFAOYSA-M
assay
≥98% (HPLC)
form
solid
solubility
water: soluble
storage temp.
2-8°C
Quality Level
Application
Metabolomics research
Microbiome research
Microbiome research
General description
Potassium phenyl sulfate is the salt of gut metabolite phenol sulfate.It is biosynthesized from phenol and phosphoadenosine phosphosulfate through the action of the enzyme sulfotransferase 1A1 in the liver. Also, it induces reactive oxygen species (ROS) production and decreases glutathione levels, rendering cells vulnerable to oxidative stress.
Other Notes
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Takeo Edamatsu et al.
PloS one, 13(2), e0193342-e0193342 (2018-02-24)
In chronic kidney disease patients, oxidative stress is generally associated with disease progression and pathogenesis of its comorbidities. Phenyl sulfate is a protein-bound uremic solute, which accumulates in chronic kidney disease patients, but little is known about its nature. Although
Koichi Kikuchi et al.
Nature communications, 10(1), 1835-1835 (2019-04-25)
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, increase with the progression of diabetes in
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