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Merck
CN

SMB00981

2-Hydroxymelatonin

≥95% (HPLC)

Synonym(s):

2-OH MEL, 2-OHM, 2-OHMET, 2OHM, N-[2-(2,3-Dihydro-5-methoxy-2-oxo-1H-indol-3-yl)ethyl]acetamide, N-[2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide, AMIO

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O3
CAS Number:
Molecular Weight:
248.28
UNSPSC Code:
12352205
NACRES:
NA.21
MDL number:
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Quality Level

assay

≥95% (HPLC)

form

solid

storage temp.

2-8°C

SMILES string

[nH]1c2c(c(c1O)CCNC(=O)C)cc(cc2)OC

InChI key

CIEAUFSGHUWAMC-UHFFFAOYSA-N

General description

Melatonin (MT) is metabolized into several derivatives, including N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N1-acetyl-5-methoxykynuramine (AMK), 6-hydroxymelatonin, 2-hydroxymelatonin, 3-hydroxymelatonin, and cyclic 3-hydroxymelatonin. MT and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants.

Application

Metabolomics research

Other Notes

For additional information on our range of Biochemicals, please complete this form.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Anis Ali Shah et al.
Chemosphere, 243, 125308-125308 (2019-11-14)
Cadmium level is continuously increasing in agricultural soils mainly due to anthropogenic activities. Cadmium is one of the most phytotoxic metals in the soils. The present study investigates the possible role of 2-hydroxymelatonin (2-OHMT) in assuagement of Cd-toxicity in cucumber
Sung Ho Lee et al.
Biochemical and biophysical research communications, 527(4), 941-946 (2020-05-23)
2-Hydroxymelatonin is a metabolite produced when melatonin 2-hydroxylase catalyzes melatonin. Recent studies have reported the important roles of melatonin in bone metabolism. However, the roles of 2-hydroxymelatonin in bone metabolism remains poorly understood. The purpose of this study is to
Kyoungwhan Back
The Plant journal : for cell and molecular biology, 105(2), 376-391 (2020-07-10)
Melatonin is a multifunctional biomolecule found in both animals and plants. In this review, the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in plants is summarized. Tryptamine 5-hydroxylase (T5H), which catalyzes the conversion of tryptamine into



Global Trade Item Number

SKUGTIN
SMB00981-5MG04065266768183
SMB00981-25MG04065266768176