SMB01324
Cyclo(His-Pro)
Synonym(s):
Cyclo(L-histidyl-L-proline), Cyclo(histidyl-proline), Cyclo(prolylhistidine), Histidylproline diketopiperazine, Histidylproline dioxopiperazine, CHP
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C11H14N4O2
CAS Number:
Molecular Weight:
234.25
UNSPSC Code:
12352209
NACRES:
NA.26
MDL number:
assay
98% (HPLC)
Quality Segment
form
solid
color
white to off-white
mp
162—164 °C
shipped in
2-8°C
storage temp.
−20°C
SMILES string
O=C1N[C@@H](Cc2cnc[nH]2)C(=O)N3CCC[C@@H]13
InChI
1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
InChI key
NAKUGCPAQTUSBE-IUCAKERBSA-N
General description
Cyclo(His-Pro) is a cyclic dipeptide consisting of the amino acids histidine (His) and proline (Pro). This small peptide forms a closed loop, with histidine and proline connected through a peptide bond. It can be found naturally in certain proteins and peptides and can also be synthesized chemically. This unique molecule is related to thyrotropin-releasing hormone and has various roles in the central nervous system. It serves as a substrate for organic cation transporters, making it essential for neuroprotection. Cyclo(His-Pro) holds promise for therapeutic applications, with the potential to counteract neuroinflammation-based degenerative conditions through both oral and parenteral administration routes. It can inhibit NF-κB nuclear accumulation and influence a range of inflammatory and stress responses, making it a valuable asset in the study of cell biology, biochemical research, and neuroprotection research.
Application
Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.
Features and Benefits
- Can be used in Metabolomics and Biochemical research
- High-quality compound suitable for multiple research applications
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Storage Class
11 - Combustible Solids
wgk
WGK 3
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.