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Y0000800

Ascorbyl palmitate

Name: Ascorbyl palmitate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):

6-O-Palmitoyl-L-ascorbic acid, L-Ascorbic acid 6-hexadecanoate, L-Ascorbyl palmitate, Ascorbic acid 6-palmitate, NSC 402451

Empirical Formula (Hill Notation):

C₂₂H₃₈O₇

CAS Number:

137-66-6

Molecular Weight:

414.53

Beilstein:

96552

MDL number:

MFCD00005377

PubChem Substance ID:

329831156

NACRES:

NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

API family

ascorbyl palmitate

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O

InChI

1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1

InChI key

QAQJMLQRFWZOBN-LAUBAEHRSA-N

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Analytical Reference Standards

Sigma-Aldrich

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Ascorbyl palmitate is a lipophilic derivative of ascorbic acid, which mainly acts as an oxygen quencher and a reducing agent for heavy metal ions. It is used as an antioxidant in both food and cosmetics industries.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

1043105

Ascorbyl palmitate, United States Pharmacopeia (USP) Reference Standard

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Simultaneous determination of ascorbyl palmitate and nine phenolic antioxidants in vegetable oils and edible fats by HPLC

Perrin C and Meyer L

Journal of the American Oil Chemists' Society, 80(2), 115-118 (2003)

Simultaneous HPLC determination of multiple components in a commercial cosmetic cream

Sottofattori E, et al.

Journal of Pharmaceutical and Biomedical Analysis, 18(1-2), 213-217 (1998)

Purification of Alaskan walleye pollock (Gadus chalcogrammus) and New Zealand hoki (Macruronus novaezelandiae) liver oil using short path distillation.

Alex C M Oliveira et al.

Nutrients, 6(5), 2059-2076 (2014-05-27)

The beneficial health effects of a diet rich in n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA) have been extensively researched in recent years. Marine oils are an important dietary source of n-3 LC-PUFA, being especially rich in two of

Ascorbyl palmitate and its synergism to tocopherols.

Karl-Heinz Wagner et al.

Forum of nutrition, 56, 347-348 (2005-04-06)

The lipophilic vitamin C derivative, 6-o-palmitoylascorbate, protects human lymphocytes, preferentially over ascorbate, against X-ray-induced DNA damage, lipid peroxidation, and protein carbonylation.

Li Xiao et al.

Molecular and cellular biochemistry, 394(1-2), 247-259 (2014-06-06)

The aim of this study was to investigate protective effects of the lipophilic vitamin C derivative, 6-o-palmitoylascorbate (PlmtVC), against X-ray radiation-induced damages including cell death, DNA double-strand breaks (DSBs), lipid peroxidation, and protein carbonylation in human lymphocytes HEV0082, and the

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