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CN

Y0000800

Ascorbyl palmitate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-O-Palmitoyl-L-ascorbic acid, L-Ascorbic acid 6-hexadecanoate, L-Ascorbyl palmitate, Ascorbic acid 6-palmitate, NSC 402451

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About This Item

Empirical Formula (Hill Notation):
C22H38O7
CAS Number:
137-66-6
Molecular Weight:
414.53
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831156
MDL number:
MFCD00005377
Beilstein/REAXYS Number:
96552

Key Documents

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Product Name

Ascorbyl palmitate, European Pharmacopoeia (EP) Reference Standard

InChI key

QAQJMLQRFWZOBN-LAUBAEHRSA-N

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O

InChI

1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

ascorbyl palmitate

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Ascorbyl palmitate is a lipophilic derivative of ascorbic acid, which mainly acts as an oxygen quencher and a reducing agent for heavy metal ions. It is used as an antioxidant in both food and cosmetics industries.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Simultaneous determination of ascorbyl palmitate and nine phenolic antioxidants in vegetable oils and edible fats by HPLC
Perrin C and Meyer L
Journal of the American Oil Chemists' Society, 80(2), 115-118 (2003)
Simultaneous HPLC determination of multiple components in a commercial cosmetic cream
Sottofattori E, et al.
Journal of Pharmaceutical and Biomedical Analysis, 18(1-2), 213-217 (1998)
Ascorbyl palmitate and its synergism to tocopherols.
Karl-Heinz Wagner et al.
Forum of nutrition, 56, 347-348 (2005-04-06)
Alex C M Oliveira et al.
Nutrients, 6(5), 2059-2076 (2014-05-27)
The beneficial health effects of a diet rich in n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA) have been extensively researched in recent years. Marine oils are an important dietary source of n-3 LC-PUFA, being especially rich in two of
Li Xiao et al.
Molecular and cellular biochemistry, 394(1-2), 247-259 (2014-06-06)
The aim of this study was to investigate protective effects of the lipophilic vitamin C derivative, 6-o-palmitoylascorbate (PlmtVC), against X-ray radiation-induced damages including cell death, DNA double-strand breaks (DSBs), lipid peroxidation, and protein carbonylation in human lymphocytes HEV0082, and the
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