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Merck
CN

G7278

Gly-Gly

BioXtra, pH 4.5-6.0 (1 M in H2O), ≥99% (titration)

Synonym(s):

Diglycine, Glycyl-glycine

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About This Item

Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
556-50-3
Molecular Weight:
132.12
EC Number:
209-127-8
UNSPSC Code:
12161700
PubChem Substance ID:
24895299
Beilstein/REAXYS Number:
1765223
MDL number:
MFCD00008130

Key Documents

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Product Name

Gly-Gly, BioXtra, pH 4.5-6.0 (1 M in H2O), ≥99% (titration)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

SMILES string

NCC(=O)NCC(O)=O

product line

BioXtra

assay

≥99% (titration)

impurities

Insoluble matter, passes filter test

ign. residue (900 °C)

≤0.05%

loss

≤0.05% loss on drying, 110 °C

pH

4.5-6.0 (1 M in H2O)

useful pH range

7.5-8.9

pKa (25 °C)

8.2

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%
As: ≤0.00001%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
NH4+: ≤0.02%
Na: ≤0.005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.072 at 280 in H2O at 1 M
≤0.075 at 260 in H2O at 1 M

Gene Information

human ... SLC15A1(6564)

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCC3911
BCCB2519
BCBW6563
BCBT5975
BCBS9136V

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Namrata D Udeshi et al.
Molecular & cellular proteomics : MCP, 12(3), 825-831 (2012-12-26)
Detection of endogenous ubiquitination sites by mass spectrometry has dramatically improved with the commercialization of anti-di-glycine remnant (K-ε-GG) antibodies. Here, we describe a number of improvements to the K-ε-GG enrichment workflow, including optimized antibody and peptide input requirements, antibody cross-linking
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 621-631 (2011-09-29)
We present a full computational description of the fragmentation reactions of protonated diglycine (H(+)GG). Relaxed potential energy surface scans performed at B3LYP/6-31 G(d) or B3LYP/6-311 + G(d,p) levels are used to map the reaction coordinate surfaces and identify the transition states (TSs) and
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 632-643 (2011-09-29)
We present a full molecular description of fragmentation reactions of protonated diglycine (H(+)GG) by studying their collision-induced dissociation (CID) with Xe using a guided ion beam tandem mass spectrometer (GIBMS). Analysis of the kinetic energy-dependent CID cross sections provides the
Daisy Bustos et al.
Molecular & cellular proteomics : MCP, 11(12), 1529-1540 (2012-06-26)
Advances in high resolution tandem mass spectrometry and peptide enrichment technologies have transformed the field of protein biochemistry by enabling analysis of end points that have traditionally been inaccessible to molecular and biochemical techniques. One field benefitting from this research
Lasse Jenner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3812-3816 (2013-02-23)
Here we present an X-ray crystallography structure of the clinically relevant tigecycline antibiotic bound to the 70S ribosome. Our structural and biochemical analysis indicate that the enhanced potency of tigecycline results from a stacking interaction with nucleobase C1054 within the
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