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Merck
CN

N9009

5-Nitro-2-furaldehyde semicarbazone

Synonym(s):

5-Nitro-2-furfural semicarbazone, Furacin, NFZ, Nitrofurazone

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About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
59-87-0
Molecular Weight:
198.14
EC Number:
200-443-1
UNSPSC Code:
12352100
MDL number:
MFCD00003225
Beilstein/REAXYS Number:
86403

Key Documents

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InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

mp

242-244 °C (lit.)

storage temp.

2-8°C

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

target_organs

male reproductive organs

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
077K2663
125K2507
121K2505
114F0566
106H2613

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Prevention of CAUTI: simple is beautiful.
Marc Leone
Lancet (London, England), 380(9857), 1891-1892 (2012-11-09)
Assessing catheter-associated urinary tract infection - Authors' reply.
Robert Pickard et al.
Lancet (London, England), 381(9877), 1536-1536 (2013-05-07)
Fengyu Deng et al.
Molecular bioSystems, 8(5), 1446-1451 (2012-02-18)
The interaction of nitrofurazone (NF) and human serum albumin (HSA) has been studied by fluorescence spectroscopy, FT-IR spectroscopy and molecular modeling methods. The results showed that the fluorescence of HSA was quenched by NF in a static quenching mechanism. Thermodynamic
James R Johnson et al.
Antimicrobial agents and chemotherapy, 56(9), 4969-4972 (2012-07-04)
Two marketed antimicrobial-coated Foley catheters were compared for in vitro diffusible and contact-dependent inhibition of 11 urinary tract infection-associated microorganisms in an adherence-biofilm assay. Nitrofurazone-coated catheters significantly outperformed silver alloy-coated catheters for inhibitory activity, according to both inoculum broth and
S Iyyam Pillai et al.
Pharmaceutical biology, 48(11), 1198-1206 (2010-09-08)
In traditional medicine propolis is widely used for the treatment of various ailments including ulcer and wound healing. The phytochemical screening of Indian propolis indicates the presence of biologically active ingredients in appreciable amounts. In the absence of systematic evaluation
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