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Merck
CN

S9512

Succinic acid

greener alternative

BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
110-15-6
Molecular Weight:
118.09
UNSPSC Code:
12352207
NACRES:
NA.71
PubChem Substance ID:
24899842
EC Number:
203-740-4
Beilstein/REAXYS Number:
1754069
MDL number:
MFCD00002789
Assay:
≥99.0% ( with NaOH, titration)
Form:
powder

Key Documents

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Quality Level

200

product line

BioReagent

assay

≥99.0% ( with NaOH, titration)

form

powder

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

density

1.564 g/cm3 at 15 °C

greener alternative category

Aligned,

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Use as a TCA (Krebs cycle) supplement in insect cell culture applications.

Other Notes

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4337
BCCP0878
BCCN6472
BCCN1502
BCCM7019

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Muhammad Fariz Ali et al.
Pathogens (Basel, Switzerland), 9(9) (2020-09-10)
To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vitro
Corey Osto et al.
Current protocols in cell biology, 89(1), e116-e116 (2020-12-16)
Measuring oxygen consumption allows for the role of mitochondrial function in biological phenomena and mitochondrial diseases to be determined. Although respirometry has become a common approach in disease research, current methods are limited by the necessity to process and measure
Monika Bambouskova et al.
Cell reports, 34(10), 108756-108756 (2021-03-11)
Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activated macrophages. We show that endogenous itaconate is
G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
Susan Jahn et al.
Biochimica et biophysica acta, 1833(12), 2879-2889 (2013-07-28)
To investigate a possible role of the nitrogen-PTS (PTS(Ntr)) in controlling carbon metabolism, we determined the growth of Escherichia coli LJ110 and of isogenic derivatives, mutated in components of the PTS(Ntr), on different carbon sources. The PTS(Ntr) is a set
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Related Content

Product Information Sheet - S9512

Product Information Sheet

Global Trade Item Number

SKUGTIN
S9512-100G04061836961459
S9512-500G04061836961466

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