AC-0344A
GRIA2 (EP387) Rabbit Monoclonal Primary Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
monoclonal
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
Application:
IHC (p)
Citations:
-
biological source
rabbit
antibody form
Ig fraction of antiserum
clone
monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
visualization
(cytoplasm/membrane)
Quality Level
General description
Glutamate receptor 2 (GRIA2) is a ligand-gated ion channel that uses L-glutamate for excitatory synaptic transmission expressed in the central nervous system. A recent gene expression profiling study reported >100 fold GRIA2 induction in solitary fibrous tumors compared with control tissues. Immunohistochemistry studies demonstrated GRIA2 positivity in the majority of solitary fibrous tumors (64-86%). Its diagnostic performance yields 64% sensitivity, 92% specificity, with 41% and 97% positive and negative predictive value, respectively for the differential diagnosis of solitary fibrous tumors versus other mesenchymal soft tissue tumors. GRIA2 may be a useful marker to identify STAT6-negative solitary fibrous tumors.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and &< 0.1% Sodium Azide
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For a copy of the IFU and CofA contact IVDorder@ABCAM.com
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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