Anti-ACAT2 (AB2) antibody produced in rabbit

ACAT2 is an acyl-coenzyme A cholesterol acyltransferase that regulates the esterification of cholesterol in cells. ACAT2 has been recommended as a treatment target for hypercholesterolemia and atherosclerosis. It has also been implicated in the inhibition of apoB secretion in liver cells.
Rabbit Anti-ACAT2 antibody recognizes bovine, human, mouse, and rat ACAT2.

The previously assigned protein identifier Q16146 has been merged into Q9BWD1. Full details can be found on the UniProt database.

Synthetic peptide directed towards the middle region of human ACAT2

Rabbit Anti-ACAT2 (AB2) antibody can be used for western blot applications at a concentration of 2 μg/ml. It can also be used for IHC applications at a concentration of 4-8 μg/ml using paraffin-embedded tissues.

Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: VLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMS

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