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Merck
CN

AV46899

Anti-NPTN antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-DKFZp686L2477, Anti-GP55, Anti-GP65, Anti-MGC102805, Anti-Neuroplastin, Anti-Np55, Anti-SDFR1, Anti-SDR1

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

42 kDa

species reactivity

human, rabbit, horse, dog, rat, bovine, guinea pig, mouse

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

NP_036560

UniProt accession no.

Q9Y639-2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NPTN(27020)

Immunogen

Synthetic peptide directed towards the middle region of human NPTN

Application

Anti-NPTN antibody produced in rabbit is suitable for western blotting at a concentration of 5μg/mL. It is also useful for immunohistochemistry at a concentration of 4-8μg/mL.

Biochem/physiol Actions

NPTN (neuroplastin) gene encodes a single-pass type I membrane protein that belongs to immunoglobulin superfamily and is expressed in brain cortex and cerebellum. It plays a crucial role in the development and maintenance of normal synaptic connections in the cerebellum.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: MEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKN

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC17022

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Hassan Marzban et al.
The Journal of comparative neurology, 462(3), 286-301 (2003-06-10)
Neuroplastin (np) 55 and 65 are immunoglobulin superfamily members that arise by alternative splicing of the same gene and have been implicated in long-term activity-dependent synaptic plasticity. Both biochemical and immunocytochemical data suggest that np55 is the predominant isoform (>95%

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