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Hepa 1-6

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 92110305, mouse liver, Not specified

Synonym(s):

Hepa 1-6 Cells

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About This Item

UNSPSC Code:
41106514
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biological source

mouse liver

packaging

tube of 5 μg 92110305-DNA-5UG
pkg of vial of cells 92110305-1VL

growth mode

Adherent

karyotype

Not specified

morphology

Not specified

products

Albumin, alpha-foetoprotein, alpha 1-antitrypsin, amylase

receptors

Not specified

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Application

Hepa 1-6 has been used to study the biodistribution of polymer hydrogel capsules for the delivery of therapeutics. It has also been used to evaluate the potential of interferon regulatory factor-1 (IRF-1) for cytokine gene therapy of hepatocellular carcinoma (HCC).

Biochem/physiol Actions

Derived from BW7756 tumour in a C57L mouse. Secretes several liver products including albumin, α-fetoprotein, α 1-antitrypin and amylase.
Mouse hepatoma

Preparation Note

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Split sub-confluent cultures (70-80%) 1:2 to 1:4 i.e. seeding at 2-5x10,000 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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