biological source
human blood
packaging
tube of 5 μg 95010509-DNA-5UG, pkg of vial of cells 95010509-1VL
growth mode
Suspension
karyotype
Not specified
morphology
Lymphoblast
products
Expresses surface Immunoglobulin M (IgM) (kappa)and secretes Immunoglobulin M (IgM) which does not bind to protein A.
receptors
Surface Immunoglobulin M (IgM) (kappa)
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cancer
shipped in
dry ice
storage temp.
−196°C
Biochem/physiol Actions
Derived from ascites fluid of a patient with Burkitt′s Lymphoma. The cells are Epstein Barr Virus Nuclear Antigen (EBNA) negative.CA46 also expresses surface IgM kappa and secretes IgM which does not bind to protein A. Twelve percent of the cells were shown to express complement receptors whereas Fc receptors were undetectable.
Human Burkitt′s Lymphoma
Preparation Note
Maintain cultures at 5-9x100,000 cells/ml; 5% CO2; 37°C.
RPMI 1640 + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).
Other Notes
Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). No licensing agreement is required when either this cell line or the DNA extracted from it are used for internal research purposes only. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.