EHU086761
MISSION® esiRNA
targeting human ALKBH8
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GGCAGCTCTCCAAGAAATTGTTCGACTCCTGAGACCAGGTGGGAAGGCACTCATTTATGTCTGGGCAATGGAACAAGAATATAATAAGCAGAAGTCCAAGTATCTTAGAGGAAACAGAAATAGCCAAGGAAAGAAAGAGGAGATGAACAGTGATACCTCAGTGCAGAGGTCACTTGTGGAGCAAATGCGTGACATGGGCAGTCGAGACTCGGCATCTTCTGTCCCCCGCATTAATGACTCTCAGGAAGGAGGATGTAATTCAAGGCAAGTTTCTAATTCCAAGCTGCCTGTTCATGTTAACAGGACTTCTTTTTATTCTCAAGATGTACTGGTTCCCTGGCACCTTAAGGGAAATCCTGATAAAGGCAAACCTGTTGAGCCATTTGGTCCCATAGGATCCC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... ALKBH8(91801)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin.
Ikumi Ohshio et al.
Biochemical and biophysical research communications, 477(3), 413-418 (2016-06-23)
Human AlkB homolog 8 (ALKBH8) is highly expressed in high-grade, superficially and deeply invasive bladder cancer. Moreover, ALKBH8 knockdown induces apoptosis in bladder cancer cells. However, the underlying anti-apoptotic mechanism of ALKBH8 in bladder cancer cells has thus far remained
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU086761-20UG | 04061831354942 |
| EHU086761-50UG | 04061828388783 |