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Merck
CN

EHU095741

MISSION® esiRNA

targeting human DMAP1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AAGTTGGGCTCCAAGAAGGTGCGGCCTTGGAAGTGGATGCCATTCACCAACCCGGCCCGCAAGGACGGAGCAATGTTCTTCCACTGGCGACGTGCAGCGGAGGAGGGCAAGGACTACCCCTTTGCCAGGTTCAATAAGACTGTGCAGGTGCCTGTGTACTCGGAGCAGGAGTACCAGCTTTATCTCCACGATGATGCTTGGACTAAGGCAGAAACTGACCACCTCTTTGACCTCAGCCGCCGCTTTGACCTGCGTTTTGTTGTTATCCATGACCGGTATGACCACCAGCAGTTCAAGAAGCGT

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... DMAP1(55929)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Wenhuan Guo et al.
The Prostate, 75(9), 976-987 (2015-03-27)
ELL-associated factor 2 (EAF2) is an androgen-regulated tumor suppressor in the prostate. However, the mechanisms underlying tumor suppressive function of EAF2 are still largely unknown. Identification of factors capable of modulating EAF2 function will help elucidate the mechanisms underlying EAF2
Liquan Cai et al.
Biochemical and biophysical research communications, 447(2), 292-298 (2014-04-15)
The tumor suppressor EAF2 is regulated by androgen signaling and associated with prostate cancer. While EAF2 and its partner ELL have been shown to be members of protein complexes involved in RNA polymerase II transcriptional elongation, the biologic roles for



Global Trade Item Number

SKUGTIN
EHU095741-20UG04061831356588
EHU095741-50UG04061828365227