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Merck
CN

EHU096601

Sigma-Aldrich

MISSION® esiRNA

targeting human JAGN1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
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description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CACCAGCACACAGGAGAAGAAGCATAAATGAAGCCTCTTTGGGGTGAAGCCTGGACATCCCATCGAATGAAAGGACACTAGTACAGCGGTTCCAAAATCCCTTCTGGTGATTTTAGCAGCTGTGATGTTGGTACCTGGTGCAGACCAGGCCAAAGTTCTGGAAAGCTCCTTTTGCCATCTGCTGAGGTGGCAAAACTATAATTTATTCCTGGTTGGCTAGAACTGGGTGACCAACAGCTATGAAACAAATTTCAGCTGTTTGAAGTTGAACTTTGAGGTTTTTCTTTAAGAATGAGCTTCGTCCTTGCCTCTACTCGGTCATTCTCCCCA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Kaan Boztug et al.
Nature genetics, 46(9), 1021-1027 (2014-08-19)
The analysis of individuals with severe congenital neutropenia (SCN) may shed light on the delicate balance of factors controlling the differentiation, maintenance and decay of neutrophils. We identify 9 distinct homozygous mutations in the JAGN1 gene encoding Jagunal homolog 1

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