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EHU111901

MISSION® esiRNA

targeting human NLRX1

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGCGGTGTCAGAATACTGGTCAGTGATCCTCAGTGAAGTCCAGCGGAACCTCAATAGCTGGGATCGGGCCCGGGTTCAGCGACACCTTGAGCTCCTACTGCGGGATCTGGAAGATAGCCGGGGTGCCACCCTTAATCCTTGGCGCAAGGCCCAGCTGCTGCGAGTGGAGGGCGAGGTCAGGGCCCTCCTGGAGCAGCTGGGAAGCTCTGGAAGCTGAGACACTGGCGGCAGGCACCTAGCTATGTGACCACTGGCCCTAAACCTTTTCCCTCTGTGGCCTCCTGGCTTGCACTGCTCCCTCTAGAAAGATTCCTTCAGGTCTGGAGGCAGAGGAATGGGCATAGCTGAGCCAGTTGCCCTCCTAGGGCATGTTTGACCAGGACTGAGTCTGGAATCTCCAAGTTAAAGATGGTGAATCAATGCTTCGGGCTTGGAGATGGAACATGCCT

Ensembl | human accession no.

ENSG00000160703

NCBI accession no.

NM_024618

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... NLRX1(79671)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Ding Ma et al.
International immunopharmacology, 71, 7-13 (2019-03-13)
Osteoarthritis (OA) is a chronic debilitating disease characterized by joint degeneration. Excessive chondrocyte apoptosis and inflammation contributes to articular cartilage destruction in OA pathology. Nucleotide-binding oligomerization domain (NOD)-like receptor X1 (NLRX1) has emerged as a critical regulator of inflammation that
Haiyan Yin et al.
Scientific reports, 7, 44311-44311 (2017-03-14)
Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present study was designed to explore whether

Global Trade Item Number

SKUGTIN
EHU111901-50UG04061828399598
EHU111901-20UG04061828625352