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EHU155691

MISSION® esiRNA

targeting human ACSF3

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGACACCGTGGTGTTTAAGGATGGCCAGTACTGGATCCGAGGCCGGACCTCAGTGGACATCATCAAGACTGGAGGCTACAAGGTCAGCGCCCTGGAGGTGGAGTGGCACCTGCTGGCCCACCCCAGCATCACAGATGTGGCTGTGATTGGAGTTCCGGATATGACATGGGGCCAGCGGGTCACTGCTGTGGTGACCCTCCGAGAAGGACACTCACTGTCCCACAGGGAGCTCAAAGAGTGGGCCAGAAATGTCCTGGCCCCGTACGCGGTGCCCTCGGAGCTGGTGCTGGTGGAGGAGATCCCGCGGAACCAGATGGGCAAGATTGACAAGAAGGCGCTCATCAGGCACTTCCACCCCTCATGACCCGGCAGACTGGGACTGCGGGTCTGGTGGGGAGCAGCAGACGTCCCCTTCACACCGAGAACCACGGGGGCCCGTCCAAGACCTGGCCTCCCTTAAA

Ensembl | human accession no.

ENSG00000176715

NCBI accession no.

NM_001127214

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... ACSF3(197322)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Biochem/physiol Actions

ACSF3 (acyl-CoA synthetase family member 3, mitochondrial) interacts with thioester and coenzyme-A, thereby activating fatty acids for the formation of acyl-coenzyme A. Acyl-coenzyme A is associated with the metabolism of fatty acids and lipids as well as ATP binding. ACSF3 is linked with non-classical CMAMMA (Combined Malonic and Methylmalonic Aciduria).

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotype.
Alfares A
Journal of medical Genetics, 48, 602-602 (2011)
Analysis of differentially expressed genes and microRNAs in alcoholic liver disease.
Liu Y
International Journal of Molecular Medicine, 31, 547-547 (2013)

Global Trade Item Number

SKUGTIN
EHU155691-20UG04061831367133
EHU155691-50UG04061828417377