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EMU019301

MISSION® esiRNA

targeting mouse Gadd45gip1

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGACCTAGACCAGCAGCAACGAAAGCGCCTAAAGGAAGAAAGACAACGACAGAAGAAGGAGGCACGAATTGCTGCTATGGCCTCTGCTGAAGCCCAGGACTCAGCAGTGTCTGGTGAACCCAGCTCCTGAAAGCTCCCTTCCCAATAAAGCCAGCTGCTGACAACCCATATTCTACACATTCTCCCTCAAGTTGTGACTTCCTGGGTCGCCCGGCTCATTCCCCAACACCTGGGCGGGAGAATCCCTCCACCTGGCTGTGTTCACACCTGGACACTAGGCCATGCCATGAACTGGGGCTTTGGGGAGAGAGAAAGGGGAATGGATGGGCAAATAATGAAGGAGCAGATGGCAGGAGAGGAGGAGGCTTCTGTTTACCAACATTAATCTCCAGTAATTAGCCAATTACCAGGGGGAGTACAGCCAAACAGACTGCATG

Ensembl | mouse accession no.

ENSMUSG00000033751

NCBI accession no.

NM_183358

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... GADD45GIP1(102060), Gadd45gip1(102060)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Shahrooz Vahedi et al.
Oncology reports, 34(1), 43-50 (2015-05-23)
Overexpression and hyperactivation of lymphocyte-specific protein tyrosine kinase (Lck) have been associated with leukemia development. We previously showed that, other than its known function as a cytoplasmic signal transducer, Lck also acts as a nuclear transcription factor in mouse leukemic
Harsha Nagar et al.
PloS one, 9(6), e98670-e98670 (2014-06-07)
Mitochondrial dysfunction has been implicated in the pathophysiology of various cardiovascular diseases. CRIF1 is a protein present in the mitochondria associated with large mitoribosomal subunits, and CRIF1 knockdown induces mitochondrial dysfunction and promotes ROS production. p66shc is a redox enzyme

Global Trade Item Number

SKUGTIN
EMU019301-50UG04061828277964
EMU019301-20UG04061828503216