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Merck
CN

EMU075701

MISSION® esiRNA

targeting mouse Depdc6

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

Key Documents

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Product Name

MISSION® esiRNA, targeting mouse Depdc6

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCGTACGCAAGGAAGACATTCACGATTGTTGGTGACGCAGTTGGCTGGGCTTTGTGGTACGAGGAAGTAAACCATGCCACATCCAGGCTGTGGACCCCAGTGGACCTGCAGCCGCTGCAGGGATGAAGGTCTGTCAGTTTGTCGTCTCTGTCAATGGCCTCAACGTGCTGAATGTAGACTACCGCACCGTGAGCAATCTGATTCTGACAGGCCCAAGGACAATTGTCATGGAAGTCATGGAGGAGTTGGACTGCTGAGCACAGAGACATCCCTGCTTGTCCCCTATCCCAGAACAACACAACAGTGGCGTGGCAAGGCTGCCAGGCACATGGATAATTGGGACATTGCAGATCTTTTCTCTGATCATATGCACCTTGTCTTTCATACGCTGTTTGAATGTGGAAGAACCAGGTTACATATCTTTAAAAACCAAAACACAGCAGGG

Ensembl | mouse accession no.

ENSMUSG00000022419

NCBI accession no.

NM_001037937

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... DEPDC6(97998), Depdc6(97998)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Falguni Das et al.
PloS one, 9(10), e109608-e109608 (2014-10-22)
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Oncology reports, 35(2), 1049-1056 (2016-01-01)
Cullin1 (Cul1) serves as a rigid scaffold in the SCF (Skp1/Cullin/Rbx1/F-box protein) E3 ubiquitin ligase complex and has been found to be overexpressed in melanoma and to enhance melanoma cell proliferation by promoting G1-S phase transition. However, the underlying mechanisms

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