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EMU193181

MISSION® esiRNA

targeting mouse Pvt1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

ATTGAGGTGGCCATTGAGAATTCAAGTGTACCTCTTGGTCCCTGATGCAGAAATGAAGTCCCCAGCATGCTCAAGAAGAGCTTCCTTGGAGGATGAGAGGCATGGGAATCTAAGTATACCCTTTAAGCGTTCCAGAAGGATTTTGAGATCCTTTCCTAAATCAAAGGTGGAATATTTGGGGATTTGGAAAATTGAGATGTGAAGCGTTGACTTAAGAGATGCCAAGTAACTCAGCAGATGTCACACAGACGATAAATAGCAAAGATGGAAGTCTTCATGCCGGAGGCAATCCTATAAGACAGCTGAGTTCTGCAGAGCTGGTAGGAGACAGACTTGCTCAGGTGATAGATCCAGCCATGATACTGACCCTAAGAGAATGAGACGCTCTGCAGAAGACAGAAGATTCCTGAAACTGGGAAAGGTGCCTAGAAATCCTGATAAGAGTGAAGAAGGAGCTGGCAGAGCAGCCTTCCTCCGCACTATGAAAGACATCCAACAGAGAGCAAGTTCCC

Ensembl | mouse accession no.

ENSMUSG00000072566

NCBI accession no.

NR_003368

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... Pvt1(19296)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Man Zhang et al.
Irish journal of medical science, 189(3), 825-834 (2020-01-05)
This study aimed to investigate the effect of long non-coding RNA-plasmacytoma variant translocation 1 (lnc-Pvt1) knockdown on regulating cell proliferation and apoptosis, and to explore its molecular mechanism in multiple myeloma (MM). Lnc-Pvt1 expression was detected in MM cell lines
Limeng Yang et al.
Molecular oncology, 14(10), 2420-2435 (2020-07-01)
Nonsense-mediated decay (NMD) proteins are responsible for the surveillance and degradation of aberrant RNAs. Suppressor with morphogenetic effect on genitalia 7 (SMG7) is an NMD complex protein and a regulator of tumor necrosis factor (TNF)-induced extrinsic apoptosis; however, this unique

Global Trade Item Number

SKUGTIN
EMU193181-20UG04061828747214
EMU193181-50UG04061828696307