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Merck
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EMU209391

MISSION® esiRNA

targeting mouse Fbxo40

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

Key Documents

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Product Name

MISSION® esiRNA, targeting mouse Fbxo40

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCAAGGAGAGGGACTTTGTTTATGGCAACCTAGAGGCTCAAGAAGTGAAAACGGTTTATACCTTCAAGATTCCCGTGAGCTACTGCGGGAAGCGAGCTCGCTTGGGAGATGCCATGTTGAAATGCAGACCAAGTGAACACAAGGCTGTGGACACTTCTGATCTGGGCATCTCTGTGGAGGACCTGCCCAAATCTGATCTCATCAAGACCACCCTCCAGTGTGCTTTGGAAAGAGAACTCAAAGGCCATGTCATCTCTGAATCCAGGAGCATCGATGGACTCTTTATGGACCTTGCCACCCAAACATACAACTTTGAGCCAGAACAGTTTTCCTCAGAGACAGTGTTGGCTGATCTCCTAGGCACTGCCCAACCCGGGGGCCTGCACGTGGAGCTCCACAGCGAGTGTGTGACTAGAAGACACAACAAAAGCAGCTCAGCTTTTACGTTCACCTGCAACAAATTCTTCCGAAGGGATGAATTTCCCCTGCACTTCAAGAATGTCCACACTGACATCCA

Ensembl | mouse accession no.

ENSMUSG00000047746

NCBI accession no.

NM_001037321

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... FBXO40(207215), Fbxo40(207215)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lot/Batch Number
JFS

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Liping Zhang et al.
American journal of physiology. Endocrinology and metabolism, 318(5), E625-E635 (2020-02-27)
Cellular mechanisms causing insulin resistance (IR) in chronic kidney disease (CKD) are poorly understood. One potential mechanism is that CKD-induced inflammation activates the signal transducer and activator of transcription 3 (Stat3) in muscle. We uncovered increased p-Stat3 in muscles of

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