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Merck
CN

GE17549853

HiTrap® MabSelect PrismA

Cytiva, 17549853, pack of 1 × 5 mL

Synonym(s):

MabSelect PrismA, FPLC column, affinity column, alkali-stable protein A, antibody capture column, chromatography column, mAb column

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About This Item

NACRES:
NB.21
UNSPSC Code:
41106500
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packaging

pack of 1 × 5 mL

manufacturer/tradename

17549853, Cytiva

General description

These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.

The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.

Features and Benefits

  • Enhanced binding capacity compared with other Protein A resins
  • Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH
  • Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
  • The PrismA protein A ligand is also available in HiTrap® Fibro and HiScreen Fibro PrismA chromatography units for ultrafast purification of mAbs.
  • Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect PrismA resins.

Legal Information

HiScreen is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
MabSelect is a trademark of Cytiva


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Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Global Trade Item Number

SKUGTIN
GE1754985304022536235158