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GW22783

Sigma-Aldrich

Anti-CD14 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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MDL number:
MFCD00164622
NACRES:
NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-22783

technique(s)

western blot: suitable

NCBI accession no.

NP_000582.1

UniProt accession no.

P08571

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CD14(929)

Immunogen

Immunogen Sequence: GI # 4557417, sequence 40-230
Recombinant CD14 antigen

Application

Anti-CD14 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

CD14 (cluster of differentiation 14) is a human gene that plays an important role in the detection of inflammatory pathogens and in the ensuing signaling of the innate immune response. It also plays an important role in recognizing tuberculosis (TB) disease and it can be used as a potential biomarker for predicting the prognosis of breast invasive ductal carcinoma with LN+ER/PR-Her2+. It is also associated with asthma, croup and allergy. The monocyte CD14 is linked to the plasma membrane by a phosphatidylinositol phospholipid.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Weifeng He et al.
PloS one, 8(9), e75366-e75366 (2013-10-03)
In clinical practice, breast cancers with lymph node positive, ER/PR-negative and overexpressed human epidermal growth factor receptor 2 (LN+ER/PR-Her2+) have high risk of recurrence, but the effective biomarkers of prognostic for this type tumor are still lacking. Since breast cancers
J Zhao et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 17(11), 1472-1478 (2013-10-16)
CD14 plays an important role in recognising the tuberculosis (TB) antigen and initiating immune response. CD14-159C/T polymorphism has been reported to be associated with susceptibility to TB in some, but not all studies. To comprehensively evaluate the correlation between CD14-159C/T
Donna C Rennie et al.
Disease markers, 35(6), 765-771 (2013-12-19)
The CD14 gene has an important role in the detection of inflammatory provoking pathogens and in the ensuing signaling of the innate immune response. We assessed the role of CD14 C-159T, G-1359T in the expression of asthma, croup, and allergy
D L Simmons et al.
Blood, 73(1), 284-289 (1989-01-01)
A cDNA clone encoding the human monocyte antigen CD14 was isolated by transient expression in COS cells of a cDNA library prepared from phorbol diester-treated HL60 cells. RNA blot analysis showed abundant expression of a single mRNA species in mature

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