L5670
Locostatin
≥98% (HPLC)
Synonym(s):
(4S)-3-[(E)-1-Oxo-2-butenyl]-4-(phenylmethyl)-2-oxazolidinone, (4S)-3-[(E)-But-2-enoyl]-4-benzyl-2-oxazolidinone, UIC-1005
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About This Item
Empirical Formula (Hill Notation):
C14H15NO3
CAS Number:
Molecular Weight:
245.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
Locostatin, ≥98% (HPLC)
InChI key
UTZAFVPPWUIPBH-QSLRECBCSA-N
SMILES string
C\C=C\C(=O)N1[C@H](COC1=O)Cc2ccccc2
InChI
1S/C14H15NO3/c1-2-6-13(16)15-12(10-18-14(15)17)9-11-7-4-3-5-8-11/h2-8,12H,9-10H2,1H3/b6-2+/t12-/m0/s1
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥30 mg/mL
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Locostatin is a cell permeable, potent inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.
Locostatin is a cell permeable, potent inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction.
Storage Class
11 - Combustible Solids
wgk
WGK 3
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