PyroPhage^® 3173 DNA Polymerase, Wild Type

Lucigen′s PyroPhage^® 3173 DNA Polymerase (patent pending) is the first thermostable enzyme to offer the superior DNA replication performance of a phage replicase. Because all current PCR enzymes are derived from bacterial or archaeal DNA repair polymerases rather than true DNA replicases, they have inherent limitations in DNA replication fidelity, robustness, and processivity. PyroPhage^® 3173 DNA Polymerase, the first replicase cloned from bacteriophage inhabiting a boiling hot spring, avoids these limitations for much more effective DNA amplification. The thermostability of PyroPhage^® 3173 DNA Polymerase makes it useful for thermocycling methods, including PCR. The potent 3′-5′ exonuclease (proofreading) activity of the Wild Type enzyme results in extraordinarily high fidelity.

PyroPhage is a registered trademark of Lucigen Corporation