N9161
Notch-2/Fc Chimera from rat
recombinant, expressed in NSO cells, ≥90% (SDS-PAGE), lyophilized powder
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About This Item
Form:
lyophilized powder
Assay:
≥90% (SDS-PAGE)
Biological source:
rat
Recombinant:
expressed in NSO cells
Mol wt:
105-115 kDa by SDS-PAGE (reducing), calculated mol wt 76.5 kDa
biological source
rat
recombinant
expressed in NSO cells
assay
≥90% (SDS-PAGE)
form
lyophilized powder
mol wt
105-115 kDa by SDS-PAGE (reducing), calculated mol wt 76.5 kDa
impurities
endotoxin, tested
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Quality Level
Gene Information
rat ... Notch2(29492)
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Analysis Note
The biological activity is measured by its ability to bind Jagged-1.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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G Weinmaster et al.
Development (Cambridge, England), 116(4), 931-941 (1992-12-01)
Notch is a cell surface receptor that mediates a wide variety of cellular interactions that specify cell fate during Drosophila development. Recently, homologs of Drosophila Notch have been isolated from Xenopus, human and rat, and the expression patterns of these
G Weinmaster
Current opinion in genetics & development, 10(4), 363-369 (2000-07-13)
The Notch signaling pathway functions in a wide variety of processes that regulate tissue patterning and morphogenesis in developing vertebrates and invertebrates. Research on the mechanism of ligand-induced Notch signal transduction has revealed a novel and essential element in the
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