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Merck
CN

PLA0009

Rabbit anti-USP7 Antibody, Affinity Purified

Synonym(s):

HAUSP, Herpes virus-associated ubiquitin-specific protease, Herpesvirus-associated ubiquitin-specific protease, TEF1, deubiquitinating enzyme 7, ubiquitin specific protease 7 (herpes virus-associated), ubiquitin thioesterase 7, ubiquitin-specific-processing protease 7

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

technique(s)

immunohistochemistry: 1:500- 1:2,000, immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000

accession no.

NP_003461.1

UniProt accession no.

Q93009

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... USP7(7874)

Immunogen

The epitope recognized by PLA0009 maps to a region between residues 1 and 50 of human Ubiquitin Specific Peptidase 7 using the numbering given in entry NP_003461.1 (GeneID 7874).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 7 (USP7) is a member of this family that has been shown to interact and stabilize p53.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lot/Batch Number
6

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Santiago Vidal et al.
Journal of virology, 94(1) (2019-10-11)
Some viruses take advantage of conjugation of ubiquitin or ubiquitin-like proteins to enhance their own replication. One example is Ebola virus, which has evolved strategies to utilize these modification pathways to regulate the viral proteins VP40 and VP35 and to

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