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PLA0018

Sigma-Aldrich

Rabbit anti-SMC2 Antibody, Affinity Purified

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Synonym(s):
CAPE, XCAP-E homolog, SMC2L1, SMC2 (structural maintenance of chromosomes 2; yeast)-like 1, SMC protein 2, SMC-2, SMC2 structural maintenance of chromosomes 2-like 1 (yeast), CAP-E, hCAP-E, chromosome-associated protein E, structural maintenance of chromosomes (SMC) family member
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

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species reactivity

human

application(s)

immunocytochemistry: 1:200-1:400
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:2,000-1:10,000

accession no.

NP_006435.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... SMC2(10592)

Immunogen

The epitope recognized by PLA0018 maps to a region between residue 1150 and the C-terminus (residue 1197) of human Structural Maintenance of Chromosomes 2 using the numbering given in entry NP_006435.1 (GeneID 10592).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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