PZ0229
PF-03246799 hydrochloride
≥98% (HPLC)
Synonym(s):
6,7,8,9-Tetrahydro-2-(phenylmethyl)-5H-pyrimido[4,5-d]azepine hydrochloride, PF-3246799 hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C15H17N3 · xHCl
CAS Number:
Molecular Weight:
239.32 (free base basis)
NACRES:
NA.77
UNSPSC Code:
51111800
PubChem Substance ID:
SMILES string
C1(CC2=NC(CCNCC3)=C3C=N2)=CC=CC=C1.Cl
InChI
1S/C15H17N3.ClH/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15;/h1-5,11,16H,6-10H2;1H
InChI key
ICVPRIZGSIUCOE-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
room temp
Quality Level
Biochem/physiol Actions
PF-3246799 is a potent serotonin 5-HT2C receptor agonist with an EC50 of 4.5 nM and minimal activity at 5-HT2A and 5-HT2B receptors. PF-3246799 had good efficacy in a preclinical canine model of stress urinary incontinence.
PF-3246799 is a potent serotonin 5-HT2C receptor agonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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