R306-05A
Rat Cardiac Fibroblasts: RCF, adult
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About This Item
NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
rat heart (Sprague Dawley, normal adult)
Growth mode:
Adherent
Morphology:
fibroblast
Relevant disease(s):
cardiovascular diseases
biological source
rat heart (Sprague Dawley, normal adult)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 42
morphology
fibroblast
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
Quality Level
General description
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Cardiac fibroblasts are the most prevalent cell type in the heart, making up 60-70 % of all cells. They are known to play key roles in the development of cardiac disease and hypertrophy. Rat Cardiac Fibroblasts provide an excellent model system to study many aspects of heart function and pathophysiology, including the regulation of cell growth, survival, inflammation, hormone secretion and metabolism.
Cardiac fibroblasts are the most prevalent cell type in the heart, making up 60-70 % of all cells. They are known to play key roles in the development of cardiac disease and hypertrophy. Rat Cardiac Fibroblasts provide an excellent model system to study many aspects of heart function and pathophysiology, including the regulation of cell growth, survival, inflammation, hormone secretion and metabolism.
Application
human heart function, neointimal formation, vascular remodeling, myocardial repair, extracellular maintenance, signaling, toxicology, gene expression, structural support for cardiomycytes, synthesis of extracellular matrix, growth factors and cytokines
Biochem/physiol Actions
Heart
Preparation Note
- 2nd passage, >500,000 cells in Rat Fibroblast Basal Medium that contains 10% FBS and 10% DMSO
- Can be cultured at least 8 population doublings
Please refer to the RCF Culture Protocol.
Other Notes
Fibroblast Basal Medium that contains 10% FBS and 10% DMSO
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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