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Merck
CN

S107

Semicarbazide hydrochloride

solid

Synonym(s):

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

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About This Item

Linear Formula:
NH2CONHNH2 · HCl
CAS Number:
563-41-7
Molecular Weight:
111.53
EC Number:
209-247-0
UNSPSC Code:
12352100
MDL number:
MFCD00013009
Beilstein/REAXYS Number:
3593642

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InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

SMILES string

Cl.NNC(N)=O

form

solid

color

white

mp

175-177 °C (dec.) (lit.)

solubility

H2O: soluble, alcohol: very slightly soluble (hot)

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Disclaimer

Photosensitive

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

target_organs

Bone

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Janaina M Zanoveli et al.
Brain research, 1294, 106-115 (2009-08-04)
Serotonin (5-HT) plays a key role in the neural circuitry mediating unconditioned and conditioned fear responses related to panic and generalized anxiety disorders. The basolateral nucleus of the amygdala (BLA) and the dorsal periaqueductal gray (dPAG) appear to be mainly
Justin G Bendall
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 26(1), 47-56 (2009-08-15)
Detecting illegal nitrofurazone treatment of food-producing animals has been undermined by the reliance on semicarbazide as a marker metabolite for analysis because, during processing, semicarbazide forms in a variety of foods not exposed to nitrofurazone by previously unexplained pathways. In
Robert McCracken et al.
Food chemistry, 136(3-4), 1562-1567 (2012-12-01)
There is evidence that semicarbazide (SEM), a marker for the banned nitrofuran nitrofurazone, can arise from other, unrelated sources. Recently, Belgium rejected 54 consignments of Bangladeshi freshwater shrimp (Macrobrachium rosenbergii), following a laboratory decision to test meat and exoskeleton combined.
Fumiko Marttila-Ichihara et al.
Journal of immunology (Baltimore, Md. : 1950), 184(6), 3164-3173 (2010-02-16)
Vascular adhesion protein-1 (VAP-1) is an endothelial, cell surface-expressed oxidase involved in leukocyte traffic. The adhesive function of VAP-1 can be blocked by anti-VAP-1 Abs and small-molecule inhibitors. However, the effects of VAP-1 blockade on antitumor immunity and tumor progression
Gongjun Yang et al.
Analytica chimica acta, 706(1), 120-127 (2011-10-15)
The use of furazolidone in food animals has been banned in European Union (EU) because of its carcinogenicity and mutagenicity on human health, but its continued misuse is widespread. Therefore, there is an urgent need for a simple, reliable, and
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