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Merck
CN

S107

Semicarbazide hydrochloride

solid

Synonym(s):

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

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About This Item

Linear Formula:
NH2CONHNH2 · HCl
CAS Number:
563-41-7
Molecular Weight:
111.53
EC Number:
209-247-0
UNSPSC Code:
12352100
MDL number:
MFCD00013009
Beilstein/REAXYS Number:
3593642

Key Documents

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InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

SMILES string

Cl.NNC(N)=O

form

solid

color

white

mp

175-177 °C (dec.) (lit.)

solubility

H2O: soluble, alcohol: very slightly soluble (hot)

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Disclaimer

Photosensitive

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

target_organs

Bone

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Gongjun Yang et al.
Analytica chimica acta, 706(1), 120-127 (2011-10-15)
The use of furazolidone in food animals has been banned in European Union (EU) because of its carcinogenicity and mutagenicity on human health, but its continued misuse is widespread. Therefore, there is an urgent need for a simple, reliable, and
N Raman et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 76(2), 161-173 (2010-04-07)
We depict the synthesis and characterization of copper(II) and zinc(II) coordination compounds of 4-(3',4'-dimethoxybenzaldehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-semicarbazone (1a), 4-(3',4'-dimethoxybenzaldehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-thiosemicarbazone (1b), 4-(3'-hydroxy-4'-nitrobenzaldehydene)2-3-dimeth yl-1-phenyl-3-pyrazolin-5-semicarbazone (1c) and 4-(3'-hydroxy-4'-nitrobenzal dehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-thiosemicarbazone (1d). All the remote compounds have the general composition [ML(2)] (M=Cu(II) and Zn(II)); L=Schiff base (1a-1d). All
Francesca Maranghi et al.
Chemico-biological interactions, 183(1), 40-48 (2009-10-01)
Semicarbazide (SEM) is a by-product of the blowing agent azodicarbonamide, present in glass jar-sealed foodstuffs mainly baby foods. The pleiotropic in vivo SEM toxicological effects suggested to explore its possible role as endocrine modulator. Endocrine effects of SEM were assessed
Haejung An et al.
Journal of AOAC International, 95(4), 1222-1233 (2012-09-14)
The method of MacMahon and Lohne for analysis of nitrofuran metabolites in shrimp was optimized to streamline the extraction processes and the LC analysis. This revised method includes 16 h of mild acid hydrolysis/derivatization followed by ethyl acetate extraction and
Qingyi Ma et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31(3), 881-893 (2010-09-30)
The systemic immune response has a vital role in propagating the damage of an intracerebral hemorrhage (ICH). Vascular adhesion protein-1 (VAP-1), a semicarbazide (SCZ)-sensitive-amine-oxidase, was found in previous studies to have a role in migration of immune cells. In this
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