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Merck
CN

S1140

Anti-Sheep IgG (whole molecule) antibody produced in rabbit

whole antiserum

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162843

Key Documents

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Product Name

Anti-Sheep IgG (whole molecule) antibody produced in rabbit, whole antiserum

biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:100,000
quantitative precipitin assay: 2.8-4.2 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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Biochem/physiol Actions

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. It is a glycoprotein and mainly helps in immune defense.
The antiserum is determined to be immunospecific for sheep IgG

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. IgG is a major class of immunoglobulin. Immunoglobulin molecules of sheep are of the λ type.

Physical form

Supplied as a liquid containing 15 mM sodium azide as preservative.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is notrecommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
treated to remove lipoproteins

Application

Anti-Sheep IgG (whole molecule) antibody produced in rabbit has been used in radioimmunoassay.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
0000094428
0000094428
0000207699
0000207699
108M4808V

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Specific IgG for cat allergens in patients with allergic conjunctivitis
Miyama A, et al.
International Ophthalmology, 35, 575-586 (2015)
J B Richards et al.
Theriogenology, 52(6), 1055-1066 (2000-03-29)
Sixteen ram lambs (5 m.o. old, 45 +/- 1.5 kg) received a control diet (50% concentrate, no locoweed, n = 4), locoweed (20% locoweed for 21 d, n = 4), MUSE (2 mL i.m. of MUSE containing 5 mg selenium
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

Related Content

Data Sheet - S1140

Instructions

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