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Merck
CN

S3316

SKF-89145 hydrobromide

>98% (HPLC), solid

Synonym(s):

4-(3,4-Dihydroxyphenyl)-6-methyl-4,5,6,7-tetrahydro­thieno[2,3-c]pyridine hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C14H15NO2S · HBr
CAS Number:
79599-92-1
Molecular Weight:
342.25
NACRES:
NA.77
PubChem Substance ID:
24899555
UNSPSC Code:
12352204
MDL number:
MFCD04040026
Assay:
>98% (HPLC)
Form:
solid
Quality level:
100

Key Documents

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Product Name

SKF-89145 hydrobromide, >98% (HPLC), solid

InChI key

WUWJEHPRFDIUMV-UHFFFAOYSA-N

SMILES string

Br[H].CN1CC(c2ccc(O)c(O)c2)c3ccsc3C1

InChI

1S/C14H15NO2S.BrH/c1-15-7-11(10-4-5-18-14(10)8-15)9-2-3-12(16)13(17)6-9;/h2-6,11,16-17H,7-8H2,1H3;1H

assay

>98% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble 10 mg/mL
H2O: soluble 4 mg/mL

Quality Level

100

Related Categories

Application

SKF-89145 was used to treat Crassostrea virginica to study the role of D1 dopamine receptors in dopaminergic neurotoxicity of manganese in gills.

Biochem/physiol Actions

D1 dopamine receptor agonist.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
032K4711
014K4605

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Samuel Anador et al.
In vivo, 32(3), 74-79 (2011-08-19)
The lateral epithelial cells of gill of Crassostrea virginica are innervated by dopamine and serotonin nerves that regulate the beating rate of their lateral cilia. Terminal release of dopamine slows down the beating rate of the cilia, while serotonin release

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