Anti-GLK antibody produced in rabbit

GLK is a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

GLK (Q8IVH8, 344-379)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 354-369 of human GLK. This antibody may react with isoforms of GLK - information can be found using acc#: Q8IVH8-2.

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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