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Key Documents

SAB1300731

Sigma-Aldrich

Anti-Phospho-Leo1-pS551 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-RDL, Anti-RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

dot blot: suitable
indirect ELISA: 1:1000

NCBI accession no.

NP_620147

UniProt accession no.

Q8WVC0

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer551)

Gene Information

human ... LEO1(123169)

General description

The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. It may be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.

Immunogen

LEO1 (NP_620147, 534-567)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S551 of human LEO1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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