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Merck
CN

SAB1309057

[KO Validated]Anti-CD44 antibody produced in mouse

[Knockout Validated]purified monoclonal antibody, buffered aqueous solution

Synonym(s):

Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLNA, FLN, FLN1

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

(Human)

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

form

liquid

mol wt

280739Da

species reactivity

human, rat, mouse

technique(s)

western blot: 1:4000
western blot: 1:500-1:2000

isotype

IgG1

storage temp.

-10 to -25°C

target post-translational modification

unmodified

Gene Information

human ... FLNA(2316)

General description

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.

Biochem/physiol Actions

Purified His-tagged FLNA protein was used to produced this monoclonal antibody.

Physical form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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