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SAB1403869

Monoclonal Anti-GLRA1 antibody produced in mouse

clone 2E7, purified immunoglobulin, buffered aqueous solution

Synonym(s):

MGC138878, MGC138879, STHE

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
2E7, monoclonal
Application:
ELISA (c), ELISA (i), WB
Citations:
-
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2E7, monoclonal

form

buffered aqueous solution

mol wt

antigen ~37.11 kDa

species reactivity

human

technique(s)

capture ELISA: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

NCBI accession no.

NM_000171

UniProt accession no.

P23415

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GLRA1(2741)

General description

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene

Immunogen

GLRA1 (NP_000162, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEE

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

This item has

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Certificates of Analysis (COA)

Lot/Batch Number
08078-2E7

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Global Trade Item Number

SKUGTIN
SAB1403869-100UG04061829621940