SAB1403982
Monoclonal Anti-INS antibody produced in mouse
clone 7C8, purified immunoglobulin, buffered aqueous solution
Synonym(s):
ILPR, IRDN
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
7C8, monoclonal
form
buffered aqueous solution
mol wt
antigen ~1.65 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
isotype
IgG3κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... INS(3630)
Related Categories
General description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. (provided by RefSeq)
Immunogen
KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)
Sequence
CFFYTPKTRREAEDLQ
Sequence
CFFYTPKTRREAEDLQ
Physical form
Solution in phosphate buffered saline, pH 7.4
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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